儿童容易忽略的药物中毒

Medicine poisoning easily overlooked in children

滴鼻净、地芬诺脂、小儿感冒药等常用来治疗儿童鼻塞、腹泻、普通感冒等,这些药物在患儿正常治疗剂量时就可以引起中毒,但因其常用、引起中毒的临床表现隐匿或者患儿家属病史提供不全,常常导致误诊甚至治疗失败.本文探讨这些药物的中毒机制及临床表现,提醒儿科医生注意这些药物中毒的临床表现和病史询问.

Naphazoline,Diphenoxylate, Over-the-counter （OTC） cough and cold medications, widely used for the symptomatic relief of nasal obstruction, diarrhea or common cold symptoms. But these medicines might cause poisoning even if utilized in recommended doses for treatment. The side effects of these medicines were neglected when they were used much more commonly. The clinical manifestation of these medicine poisoning were delitescence and children＇ s parents couldn＇t provide the whole history, so these medicine poisoning were often misdiagnosis, even lead to treatment failure. We explore the toxicities of these medicines ,discuss their mechanisms and clinical manifestation, and suggest why physicians should be more vigilant in specifically inquiring about them when evaluating an ill child.