人血白蛋白治疗老年急性大面积脑梗死临床观察

Effect of albumin prepared from human plasma on aging acute massive cerebral infarction

目的研究早期应用白蛋白治疗老年急性大面积脑梗死的临床效果。方法 42例老年急性大面积脑梗死患者随机分为对照组和观察组,对照组采用常规治疗,观察组在常规治疗基础上应用白蛋白注射液10g静滴、1次/d,连用14d,比较两组治疗前及治疗后14、28d的神经功能缺损程度评分。结果两组患者经治疗后均有不同程度好转,观察组较对照组好转更明显,28d时更为显著,差异均有统计学意义。结论早期应用白蛋白治疗老年急性大面积脑梗死,效果肯定,能显著改善预后。

Objective To study the clinical effect of albumin prepared from human plasma on aging acute massive cerebral infarction. Methods Forty-two patients of aging acute massive cerebral infarction were assigned into control group and observation group randomly. In control group conventional treatment were offerd. For those in observation group underwent albumin parenteral solution ten gram ivdrip once a day and continuing 14 days,in addition to conventional treatment. Before and 14 d,28 d after the therapy,neural function defect evaluation were assessed. Results Grades of neural function defect evaluation in observation group were lower than those in control group,and the difference was more prominent at 28 d. There were significant difference between control group and observation group. Conclusion Albumin prepared from human plasma is effcient in treating aging acute massive cerebral infarction and ameliorate the prognosis markly.