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GABA在可卡因成瘾的中枢作用机制 被引量:2

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摘要 可卡因是最强的天然中枢神经兴奋剂,其成瘾机制主要为多巴胺系统的中脑边缘通路产生的犒赏效应。GABA是中枢神经系统的重要抑制性神经递质,GABA对可卡因的作用主要通过多巴胺受体的作用完成,GABA不同亚型受体在可卡因成瘾中起不同作用,通过对GABA受体激动剂和拮抗剂的研究能够促进可卡因成瘾临床治疗的发展。
机构地区 中国医科大学
出处 《中国中医药咨讯》 2010年第17期211-211,共1页
关键词 GABA 可卡因 成瘾
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