甲氨喋呤加来氟米特联合治疗类风湿关节炎疗效分析

Armor ammonia die p rine in chem compounds Calais fluorine Mitter unites the treatment class rheumatism arthritis curative effect to analyze

目的：探讨甲氨蝶呤加来氟米特联合治疗类风湿关节炎（RA）患者的疗效及安全性.方法：选取2007年7月-2010年6月在我院就诊的90例RA患者,随机平均分为两组,对照组单用MTX药物治疗,观察组联合使用MTX与LEF药物治疗,治疗l2周后观察相关指标.结果：两组患者关节压痛数、握力、ESR等指标上有显著性差异（P〈0.05）,两组不良反应发生率也有统计学意义（P〈0.01）.结论：MTX与LEF联合药物治疗类风湿关节炎疗效显著,临床所致不良反应较少,值得临床进一步推广和应用.

Objective：Discussion armor ammonia pterin Calais fluorine Mitter unites the treatment class rheumatism arthritis （RA） patient＇s cura7 tive effect and the security. Methods： Selects in July, 2007 -- June, 2010 in my courtyard seeing a doctor 90 example RA patient, the stochastic average divides into two groups, the control group only uses the MTX medicine treatment, the observation group to use MTX and the LEF medicine treatment jointly,after treats the 12 week to observe the index of correlation. Results：Two group of patient joint tenderness number,grasps targets and so on in strength,ESR has the significance difference （P〈0.05） ,two groups responded not good the formation rate also has statistics significance （P〈0.01）. Conclusion： MTX and the LEF union medicine treatment class rheumatism arthritis curative effect is remarkable, the clinical result responded not good few, is worth clinical further promoting and the application.