肝移植术后胆道并发症分析与预防被引量：6

Analyze and prevent the biliary complications after liver transplantations

下载PDF

导出

摘要目的探讨肝移植术后胆道并发症的相关因素。方法回顾性研究100例原位肝移植患者的临床资料,采用单因素分析及Logistic多因素回归模型分析各危险因素的分布。结果9例患者确诊为肝移植术后胆道并发症,7例治愈,2例因感染死亡。胆道并发症发生率为9%,单因素分析及非条件Logistic多元回归分析表明胆道血供和胆道吻合口直径与肝移植后胆道并发症的发生密切相关。结论胆道并发症是肝移植术后常见并发症之一,缺血性损伤和吻合口大小是肝移植术后胆道并发症的重要原因,及时预防、诊断、处理胆道并发症将明显地提高肝移植患者的生活质量和生存期。 Objective To discuss the relevant factors of biliary complications after liver transplantations.Methods One hundred patients who received liver transplantations were reviewed retrospectively.And the risk factors were analyzed by univariate analysis and multivariate logistic regression analysis.Results Biliary complications after liver transplantations were diagnosed in 9 patients.Seven patients were cured and 2 patients died due to infection.The incidence for biliary complications was 9%.The univariate analysis and multivariate logistic regression analysis showed that the damage of blood supply and the diameter of biliary anastmosis were significantly associated with biliary complications after liver transplantations. Conclusion Biliary complications are common after liver transplantations.Ischemic injury and the diameter of anastmosis are risk factors for biliary complications after liver transplantations.Timely prevention,diagnosis and treatment will significantly increase quality of life and survival time of patients.

作者王德盛窦科峰宋振顺岳树强陶开山何勇帝振宇刘正才曹大勇

机构地区第四军医大学西京医院肝胆外科

出处《胃肠病学和肝病学杂志》 CAS 2010年第8期749-751,共3页 Chinese Journal of Gastroenterology and Hepatology

基金第四军医大学西京医院高新技术资助项目(XJGX0711M09)

关键词肝移植手术后并发症胆道预防 Liver transplantation Postoperative complications Biliary Prevention

分类号 R657.3 [医药卫生—外科学]

引文网络
相关文献

参考文献8

1Safdar K, Atiq M, Stewart C, et al. Biliary tract complications after liver transplantation [ J]. Expert Rev Gastroenterol Hepatol, 2009, 3 (2) : 183-195.
2Greif F, Bronsther OL, Van Thiel DH, et al. The incidence, timing, and management of biliary tract complications after orthotopic liver transplantation [J]. Ann Surg, 1994, 219( 1 ) : 40-45.
3Buck DG, Zajko AB. Biliary complications after orthotopic liver transplantation [J].Tech Vasc Interv Radiol, 2008, 11(1): 51-59.
4Wojcicki M, Milkiewicz P, Silva M. Biliary tract complications after liver transplantation: a review [ J ]. Dig Surg, 2008, 25 (4) : 245 -257.
5Sanchez-Urdazpal L, Gores GJ, Ward EM, et al. Ischemic-type biliary complications after orthotopic liver transplantation [ J ]. Hepatology, 1992, 16(1) : 49-53.
6Scotte M, Dousset B, Calmus Y, et al. The influence of cold ischemia time on biliary complications following liver transplantation [ J ]. J Hepatol, 1994, 21 (3) : 340-346.
7Sharma S, Gurakar A, Jabbour N. Biliary strictures following liver transplantation: past, present and preventive strategies [ J ]. Liver Transpl, 2008, 14(6) : 759-769.
8Kobayashi T, Sato Y, Yamamoto S, et al. Long-term follow-up study of biliary reconstructions and complications after adult living donor liver transplantation: feasibility of duct-to-duct reconstruction with a T-tube stent [ J]. Transplant Proc, 2009, 41 ( 1 ) : 265-267.