活体肝移植应用脂肪肝供肝的疗效分析
摘要
目前,活体肝移植呈增多趋势,在活体供者评估过程中,经常遇到脂肪肝供肝的应用问题。有研究认为尸体供肝脂肪变若为中度脂肪肝(肝细胞脂肪浸润程度〈60%)以下的可以安全利用,重度脂肪肝供体将增加受体风险[1-2]。但对于亲体肝移植脂肪肝供肝的应用问题研究结论并不一致。
出处
《天津医药》
CAS
北大核心
2010年第8期727-728,共2页
Tianjin Medical Journal
参考文献6
-
1Müllhaupt B,Dimitroulis D,Gerlach JT,et al.Hot topies in liver transplantation:organ allocation-extended criteria donor-living donor liver transplantation[J].J Hepatol,2008,48(Suppl 1):S58-67.
-
2朱志军,高伟,孟醒初,张雅敏,蒋文涛,张建军,张玮晔,沈中阳.脂肪沉着供肝在肝脏移植中的应用[J].中华肝胆外科杂志,2005,11(9):627-629. 被引量:7
-
3Frongillo F,Avolio AW,Nure E,et al.Quantification of degree of steatosis in extended criteria donor grafts with standardized histologic techniques:implications for graft survival[J].Transplantation,2009,41(04):1268-1272.
-
4Angele MK,Rentsch M,Hartl WH,et al.Effect of graft steatosis on liver function and organ survival after liver transplantation[J].Am J Surg,2008,195(02):214-220.
-
5Urena MA,Moreno Gonzalez E,Romero CJ,et al.An approach to the rational use of steatotic donor livers in liver transplantation[J].Hepatogastroenterology,1999,46(26):1164-1173.
-
6Cho JY,Suh KS,Kwon CH,et al.The hepatic regeneration power of mild steatotic grafts is not impaired in living-donor liver transplantation[J].Liver Transpl,2005,11(2):210-217.
二级参考文献10
-
1D'Alessandro AM, Kalayoglu M, Sollinger H, et al. The predictive value of donor liver biopsies for the development of primary nonfunction after orthotopic liver transplantation. Transplantation,1991,51: 157-163.
-
2Deborab V, Taras K, Dorotby P. et al. Clinical experience gained from the use of 120 steatotic donor livers for orthotopic liver transplantation. Liver Transpl,2003,9: 500-505.
-
3Adam R, Reynes M, Johann M, et al. The outcome of steatotic grafts in liver transplantation. Transplant Proc, 1991,23 : 1538-1540.
-
4Markin RS, Wisecarver JL, Radio SJ, et al. Frozen section evaluation of donor livers before transplantation. Transplantation, 1993,56 : 1403-1409.
-
5Fishbein T, Fiel M, Emre S, et al. Use of livers with microvesicular fat safely expands the donor pool. Transplantation, 1997,64:248-251.
-
6Chui A, Haghighi K, Painter D, et aL Donor fatty (steatotic)liver allografts in orthotopic liver transplantation. Transplant Proc.1999,31: 3286-3287.
-
7Strasberg S, Howard T, Molmenti E, et al. Selecting the donor liver: risk factors for poor function after orthotopic liver transplantation. Hepatology, 1994,20 : 829-838.
-
8Urena MA, Ruiz-Delgado FC, Gonzalez EM, et al. Assessing risk of the use of livers with macro and microsteatosis in a liver transplant program. Transplant Proc, 1998,30 : 3288-3291.
-
9Rinella ME, Alonso E, Rao S, et al. Body mass index as a predictor of hepatic steatosis in living liver donors. Liver Transpl,2001,7:409-414.
-
10Fukumori T, Ohkohchi N, Tsukamoto S, et al. Why is fatty liver unsuitable for transplantation? Deterioration of mitochondrial ATP synthesis and sinusoidal structure during cold preservation of a liver with steatosis. Transplant Proc, 1997,29: 412-415.
共引文献6
-
1史瑞,蒋文涛,朱志军,郑虹,邓永林,潘澄,沈中阳.脂肪肝供肝活体肝移植的术前评估[J].中国组织工程研究与临床康复,2010,14(31):5725-5728. 被引量:2
-
2崔子林,傅志仁,朱志军,张雅敏,张建军,蒋文涛,杨涛,淮明生,张威.活体肝移植中轻度脂肪变性供肝的应用[J].中国组织工程研究与临床康复,2011,15(18):3243-3246. 被引量:1
-
3叶啓发,明英姿,赵杰,彭贵主,张毅.64例脂肪变性供肝临床肝移植疗效分析[J].中华肝胆外科杂志,2013,19(2):105-107. 被引量:10
-
4滕大洪,郑虹,邓永林,孙丽莹,潘澄,刘懿禾,宋红丽,蒋文涛,沈中阳.供体因素对肝细胞癌肝移植预后的影响[J].中华外科杂志,2013,51(5):454-455. 被引量:1
-
5江艺,潘凡.重视肝移植中脂肪肝供肝质量的评估的问题[J].中华普通外科学文献(电子版),2014,8(4):1-2. 被引量:1
-
6杨和君,吕立志.脂肪肝供肝对肝移植术后早期肝功能的影响[J].中华解剖与临床杂志,2014,19(6):492-496.
-
1朱银芳.以转氨酶升高为主要临床表现的多发性肌炎4例分析[J].中国误诊学杂志,2007,7(5):1136-1137. 被引量:1
-
2万彩凤.多发伤患者红细胞输注后的效果评价[J].中国现代医生,2011,49(22):43-44. 被引量:1
-
3倪少滨,于江,于文溪,吕德滨.尸体肾移植应用环孢素A的初步体会[J].哈尔滨医药,1990,10(2):5-7.
-
4邢广君,傅耀文,肖连陞,史明,赵玉千.环孢素在尸体肾移植应用的长期效果[J].吉林医学,1991,12(2):102-103.
-
5姚士伟,钱芳,崔培林.急性颅脑损伤患者转氨酶的变化及临床意义[J].中国医师杂志,2011,13(3):392-393. 被引量:3
-
6沈洁,张卫中,谢觉醒.腹腔镜胆囊切除术前后血清转氨酶的变化[J].现代实用医学,2005,17(5):280-281. 被引量:1
-
7李永芳,刘杰,车胜荣.肾脏移植后环孢菌素A的应用问题[J].青海医学院学报,1996,17(4):280-281.
-
8李宁.糖尿病围手术期TPN应用问题[J].中国实用外科杂志,1999,19(3):139-141. 被引量:51
-
9孙晓毅,李白莉.甲状腺机能亢进术前准备及β受体阻滞剂的应用问题[J].普外临床,1991,6(6):375-377.
-
10刘洋,张洪义,赵刚.高脂血症患者腹腔镜胆囊切除术后ALT和AST水平的变化及意义[J].临床肝胆病杂志,2016,32(3):526-529. 被引量:2