摘要
尽管外科手术仍然是胃癌治疗的主要手段,但总体的治疗模式已经发生了明显的改变：从解剖学为基础的手术走向以解剖学、肿瘤生物学及免疫学为基础的手术;从只重视切除肿瘤到以切除原发肿瘤及受侵器官,彻底清除区域淋巴结及杀灭腹腔脱落癌细胞的外科治疗;从单一的手术进入围手术期治疗加规范化手术的新治疗模式.
The therapeutic mode has changed over time, although surgery remains the main treatment of choice for gastric cancer. Surgery alone provides long-term survival in only 30% of patients with advanced stages because of the high risk of recurrence and metastasis. Multimodal strategies including neoadjuvant and （or） adjuvant protocols combined with surgery have significantly improved the prognosis of patients with gastric cancer. In particular, perioperative chemotherapy has become the new standard for treatment of patients with advanced gastric cancer. Adjuvant therapy should be carefully discussed after surgical resection, mainly in patients with large lymph node-positive tumors when neoadjuvant therapy can not be carried out. This article reviews the relevant literature on the multidisciplinary management of gastric cancer, and discusses strategies to improve the efficacy of locoregional failures.
出处
《中华消化外科杂志》
CAS
CSCD
2010年第4期241-243,共3页
Chinese Journal of Digestive Surgery
基金
首都医学发展科研基金（2007-2051）
十一五国家科技支撑计划（2006BAI02A06）
国家高技术研究发展专项（2006AA02A402）
关键词
胃肿瘤
多学科
诊断
治疗
Gastric neoplasms
Multidisciplinary
Diagnosis
Therapy
