新疆维吾尔族后循环梗死患者踝臂指数与颅内动脉狭窄的相关性研究

Correlation of Ankle-brachial Index with Intracranial Arteriostenosis in Uygur Patients with Posterior Circulation Infarct in Xinjiang

目的探讨新疆维吾尔族后循环梗死患者踝臂指数与颅内动脉狭窄的关系。方法对入选患者进行资料采集,测量踝臂指数,联合使用经颅多普勒超声(TCD)和磁共振血管成像(MRA)诊断颅内动脉狭窄。结果共收集维吾尔族后循环梗死患者62例,其中颅内动脉狭窄者33例,无颅内动脉狭窄者29例。颅内动脉狭窄组和无颅内动脉狭窄组患者比较,糖尿病和高血脂的发生率间差异有统计学意义(P<0.01);无狭窄组和单支狭窄组患者分别与三支狭窄组患者比较,ABI异常率间差异有统计学意义(P<0.05),ABI值间差异也有统计学意义(P<0.05);糖尿病和ABI异常是导致颅内动脉多支病变的危险因素糖尿病:OR值5.331,95%CI为(1.055,26.947),P=0.043;ABI异常:OR值5.455,95%CI为(1.208,24.624),P=0.027。结论 ABI与颅内动脉狭窄有关,随着颅内狭窄动脉的数量增多,ABI值逐渐降低;有糖尿病史和ABI异常的患者容易合并颅内动脉多支病变。

Objective To explore the relationship between ankle-brachial index（ABI） and intracranial arteriostenosis in Uygur Patients with posterior circulation infarct in Xinjiang. Methods Data of enrolled patients were collected, ABI detected, intracranial arteriostenosis diagnosed by transcranial Doppler ultrasound （TCD） and magnetic resonance angiography （MRA）. Results Sixty-two Uygur patients with posterior circulation infarct were enrolled, including 33 with intracranial arteriostenosis and 29 without, and there was significant difference in incidence of diabetes and hyperlipemia between 2 groups （P0.01）. Group stenosis or group single-arteria stenosis were significantly different from group 3-arteria stenosis in ABI abnormality rate （P0.05）, and there was difference in ABI value （P0.05）. Diabetes and ABI abnormality were risk factors inducing intracranial multivessel disease diabetes： OR=5.331,95% CI（1.055,26.947）,P=0.043;ABI abnormalityOR=5.455,95% CI（1.208,24.624）,P=0.027. Conclusion ABI is associated with intracranial arteriostenosis. With increase of arteries, ABI decreased gradually. Patients having history of diabetes and ABI abnormality are more often complicated by intracranial artery multi-vessel disease.