23例肾动脉支架植入治疗肾血管性高血压疗效探讨

Effectiveness of stent Placement in Patients with Hypertension Caused by Renal Artery Stenosis

目的探讨肾动脉内支架置入术(percutaneous transluminal renal artery stenting PTRAS)治疗肾血管性高血压的疗效。方法对23例肾动脉狭窄(renal artery stenosis,RAS)患者进行了肾动脉支架置入术,并观察手术对患者血压的影响。结果 23例患者均成功置入肾动脉支架。患者收缩压由术前的180.2±42.3mmHg降至术后的136.5±23.3mmHg(术后第二天血压)(P<0105),舒张压由术前的115.2±32.1mmHg降至术后的85.21±34.3mmHg(术后第二天血压)(P<0.05),服用降压药物种类由术前的2.8±0.3种减少为术后的1.3±0.2种(P<0105)。结论 PTRAS可有效降低肾血管性高血压患者血压。

Objective To study the effectiveness of stent placement in patients with hypertension caused by renal artery stenosis. Methods Twenty-three patients with poorly controlled hypertension for severe renal artery stenosis were treated by stents. Their blood pressure were measured at baseline and during follow-up. Results Stents placement were performed on 23 patients successfully. After the procedure,the mean systolic blood pressure of the patients was reduced from 180.2±42.3 mmHg to 136.5±23.3mmHg（the second day of the procedureP〈0.05） . The mean diastolic blood pressure of the patients was reduced from 115.2±32.1mmHg to 85.21±34.3mmHg（the second day of the procedure）（P〈0.05） . The number of hypertensive drugs sorts was reduced from 2.8±0.3 to 1.3±0.2（P〈0.05） . Conclusions Renal artery stenting for renal artery stenosis has a benefi cial effect on blood pressure control.