冲击波碎石前后对肾功能影响的MR研究

Evaluation of kindey function before and after Extracorporeal shock wave therapy with Magnetic resonance imaging

目的通过弥散成像(DWI)对体外冲击波碎石解除结石性急性输尿管梗阻前后肾脏功能的变化进行分析评价。方法 30例通过超声或CT平扫诊断的急性结石性输尿管梗阻患者(女7名和男23名,年龄为31-76岁,平均年龄53.8岁)。所有患者采用体外冲击波碎石术(ESWL)进行碎石治疗,在治疗前后均行双侧肾磁共振弥散加权成像。应用磁共振分析软件测量ADC值,并对结果进行统计学分析,P值小于0.05具有统计学意义。结果 ESWL治疗前,梗阻侧肾脏的ADC值小于无梗阻侧;行ESWL治疗后梗阻侧肾脏的ADC值较治疗前升高至接近正常水平。结论 DWI可以对结石性输尿管梗阻患者行ESWL治疗前后肾脏功能的变化进行评估,为临床肾功能改变提供客观有效的评价标准。

Objective To evaluate the change of kindey function before and after the treatment of ESWL with DWI in patients with acute ureteral obstruction due to calculus. Materials and Methods Thirty patients（7 women,23 men;ages 31-76 years,mean 53.8 years） with acute ureteral obstruction due to calculus diagnosed at unenhanced computed tomography were given the treatment of ESWL,and Diffusion-weighted MR imaging was performed before and after ESWL to all patients. Results Compared with contralateral unobstructed kidneys,the ADC of obstructed kidneys was lower before ESWL;And after the treatment,the ADC was increased.Conclusion： DWI can evaluate the change of kindey function before and after the treatment of ESWL with acute ureteral obstruction due to calculus,and provide information to help the clinical treatment .