酚妥拉明在高原喘憋性肺炎合并心衰中的应用(附74例临床分析)

Application of Phentolamine for treating of altitude asthmoid pneumonia combined with heart failure

对甘南高原地区1994－1996年冬春季发病的136例喘憋性肺炎合并心衰随机分为三组：Ⅰ组应用酚妥接明加西地兰联合治疗；Ⅱ组单用酚妥拉明；Ⅲ组单用西地兰。结果Ⅰ组疗效明显优于Ⅱ组、Ⅲ组，临床各项观察指标间（除住院天数外），差异均有高度显著性（P＜0．01）。说明联合用药在高原地区治疗喘憋性肺炎合并心衰有一定的临床实用价值。本文结果还表明，藏族与回族，汉族与回族间对药物反应的差异均有高度显著性（P均＜0．01）。

136 cases children of asthmoid pneumonia combined with heart failure, who were attacked in winter and spring of 1994~1996 in Gannan high altitude, are divided into 3 groups randomly. Group Ⅰ: treated with Phentolamine combined with Cedilanid;Group Ⅱ: with Phentolarnine only; GroupⅢ: with Cedilanid only. The results show:curative effect of group Ⅰ is obviously better than group Ⅱ and Ⅲ;between all the clinical observation indexes (except duration of hospitalization) are with highly significantdifference (all P＜0. 01). It shows that combined treatment for treating of asthmoid pneumonia with heart failure in high altitude district has a certain clinical practical value. The results also show that the drug reaction between Tibetan and Hui,Han and Hui nationality are with highly significant difference (all P＜0.005).