米诺环素与聚甲酚磺醛治疗宫颈沙眼衣原体感染的比较

Minocycline vs policresulen in treating Chlamydia trachomatis cervicitis

目的：观察米诺环素和聚甲酚磺醛对沙眼衣原体感染及宫颈糜烂的疗效。方法：对１１９例宫颈糜烂（年龄３２ａ±ｓ７ａ）中３０例衣原体阳性者分组治疗。一组（１４例）用米诺环素，２００ｍｇ（１００ｍｇ／粒），ｐｏ，ｑｄ×５ｄ。另一组（１６例）用聚甲酚磺醛，其浓缩液棉拭子插入宫颈管内２～３ｃｍ，停留２ｍｉｎ，再将浓缩液浸湿棉块敷宫颈糜烂面３ｍｉｎ，１ｗｋ重复治疗１次。２组均停药７ｄ复查。结果：米诺环素、聚甲酚磺醛治疗衣原体有效率分别为１００％和９４％（Ｐ＞０．０５），对宫颈糜烂有效率为７１％和８１％（Ｐ＞０．０５）。结果：米诺环素、聚甲酚磺醛对衣原体感染及宫颈糜烂均有较好疗效。

AIM: To observe the efficacy of minocycline and policresulen in treating Chlamydia trachomatis cervicitis. METHODS: Thirty Chlamydia trachomatis positives of 119 cervix erosion patients (age 32 a±s 7 a) were divided into 2 groups. One group (14 patients) was treated with minocycline hydrochloride 200 mg (100 mg/tablet), po[WTBZ], qd×5 d. The other group (16 patients) was treated with policresulen condensed liquid on cotton swab inserted into cervix 2_3 cm for 2 min and then on cotton swab applied on cervix erosion surface for 3 min, qw×2. RESULTS: When the treatment was withdrawal after 7 d, the effective rates of minocycline and policresulen groups were 100% and 94% (P > 0.05) in treating Chlamydia trachomatis cervicitis, 71% and 81%(P>0.05) in treating cervix erosion, respectively. CONCLUSION: Both minocycline and policresulen were effective in treating Chlamydia trachomatis cervicitis and cervix erosion.