期刊文献+

糖尿病胃轻瘫患者血浆Ghrelin水平的变化 被引量:8

下载PDF
导出
摘要 目的:探讨糖尿病胃轻瘫患者空腹血浆Ghrelin水平的变化及影响因素。方法:分别测定30例糖尿病胃轻瘫患者(DG组)、30例糖尿病无并发症患者(DM组)及20例健康对照人群(NC组)的血压、体质指数(BMI)、空腹血浆Ghrelin值、胰岛素和血糖值,计算胰岛素抵抗指数(HOMA-IR),并对其结果进行分析。结果:DG组空腹血浆Ghrelin水平明显低于DM组和NC组,差异有显著性(P<0.05);Ghrelin水平与空腹血糖水平以及HOMA-IR呈负相关。结论:糖尿病胃轻瘫患者存在血浆Ghrelin水平低下,可能与多种因素有关,从而影响胃的排空以及胃动力。
作者 洪兵 王旭
出处 《实用医学杂志》 CAS 北大核心 2010年第17期3170-3172,共3页 The Journal of Practical Medicine
  • 相关文献

参考文献3

二级参考文献51

  • 1徐珞,陶尚敏.神经降压素抗实验性胃溃疡作用初步探讨[J].中国行为医学科学,2005,14(9):775-776. 被引量:7
  • 2[18]Talley NJ.Serotoninergic neuroenteric modulators.Lancet 2001; 358:2061-2068
  • 3[19]Gershon MD.Review article:roles played by 5-hydroxytryptamine in the physiology of the bowel.Aliment Pharmacol Ther 1999; 13 Suppl 2:15-30
  • 4[20]Berthoud HR,Kressel M,Raybould HE,Neuhuber WL.Vagal sensors in the rat duodenal mucosa:distribution and structure as revealed by in vivo DiI-tracing.Anat Embryol(Berl) 1995; 191:203-212
  • 5[21]Foxx-Orenstein AE,Kuemmerle JF,Grider JR.Distinct 5-HT receptors mediate the peristaltic reflex induced by mucosal stimuli in human and guinea pig intestine.Gastroenterology 1996; 111:1281-1290
  • 6[22]Blackshaw LA,Grundy D.Effects of 5-hyctroxytryptamine(5-HT) on the discharge of vagal mechanoreceptors and motility in the upper gastrointestinal tract of the ferret.J Auton Nerv Syst 1993; 45:51-59
  • 7[23]Glatzle J,Sternini C,Robin C,Zittel TT,Wong H,Reeve JR Jr,Raybould HE.Expression of 5-HT3 receptors in the rat gastrointestinal tract.Gastroenterology 2002; 123:217-226
  • 8[24]Grider JR,Kuemmerle JF,Jin JG.5-HT released by mucosal stimuli initiates peristalsis by activating 5-HT4/5-HT1preceptors on sensory CGRP neurons.Am J Physiol 1996; 270:G778-G782
  • 9[25]Date Y,Murakami N,Toshinai K,Matsukura S,Niijima A,Matsuo H,Kangawa K,Nakazato M.The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats.Gastroenterology 2002;123:1120-1128
  • 10[26]Yakabi K,Ro S,Onouhi T,Tanaka T,Ohno S,Miura S,Johno Y,Takayama K.Histamine mediates the stimulatory action of ghrelin on acid secretion in rat stomach.Dig Dis Sci 2006; 51:1313-1321

共引文献26

同被引文献98

引证文献8

二级引证文献51

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部