华蟾素治疗癌痛的临床应用研究进展

Clinical application progress of cinobufagin to cancer pain relief

华蟾素是从中华大蟾蜍全皮中提取的主要有效组分,华蟾素注射液作为一种新型的抗肿瘤制剂,广泛用于肝癌、肺癌等多种恶性肿瘤的治疗及肿瘤相关并发症的辅助治疗,且毒副作用低,尤其在治疗肝癌、胃癌、肺癌以及骨转移癌等引起的疼痛方面,显示出较好的临床应用价值。对华蟾素及其注射液在治疗癌痛的临床应用进行综述。

Cinobufagin is an active ingredient ofBufo bufo gargarizans Cantor. As a new anticancer drug, Cinobufagin Injection has been widely used clinically in treatment of carcinoma such as hepatic carcinoma and lung cancer. It is reported that cinobufagin plays an important role in cancer pain relief and has little toxic side effects. Cinobufagin shows good clinic values, especially in relieving cancer pain induced by hepatocarcinoma, gastric cancer, lung cancer and bone cancer. This paper has summarized the recent research progress on the anti-cancer pain relief of cinobufagin injection.