摘要
目的了解贵州省志贺菌菌型分布及耐药情况。方法对77株菌痢标本采用WHO推荐的美国临床实验室标准化委员会(NCCLS)规定的药敏试验(改良K-B法)进行耐药性分析。结果 4个监测地区的77株菌,经血清分型,结果宋内52株占67.53%,福氏25株占32.47%。福氏亚型F3a10株占40.00%、F2a9株占36.00%、F1a3株占12.00%、福氏X变种2株占8.00%、F2b1株占4.00%。77株志贺菌均有不同程度的耐药。结论 77株志贺菌对10种抗生素已有不同程度的耐药,耐药率达6.49%～100.00%,且已产生多重耐药现象,提示贵州志贺菌耐药情况已较为严重,尤其是对第三代喹诺酮类药物环丙沙星已开始产生耐药。
Objective To obtain the situation of Guizhou Province Shigella＇s distribution and drug resistance.Method Analysis of the drug resistance of 77 bacillary dysentery specimens with medicine sensitive experiment （improved K-B）,for American Clinical Laboratory Standardization Committee （NCCLS） recommendated by WHO.Results 77 specimens of 4 monitor areas,by the blood somatotype,S.sonneri 52 accounts for 67.53%,S.flexneri 25 accounts for 32.47%.S.flexneri hypotype F3a 10 accounts for 40.00%,F2a 9 accounts for 36.00%,F1a 3 accounts for 12.00%,S.flexneri X variety 2 accounts for 8.00%,F2b 1 accounts for 4.00%.77 Shigella specimens had varying degree of drug resistance.Conclusions 77 Shigella specimens had varying degree drug resistance of 10 kinds of antibiotic,the rate reached to 6.49%～100.00%,and which had been multiple drug resistance,the above showed that Guizhou Shigella the drug resistance situation already seriously,especily to the third generation QNS medicine ciprofloxacin had been resistance to drug.
出处
《医学动物防制》
2010年第8期692-694,共3页
Journal of Medical Pest Control
关键词
菌痢
志贺菌
菌型
耐药性
Bacillary dysentery
Shigella
Distribution
Drug resistance
