强力宁合用丹参抗肝纤维化的疗效观察

The Clinical Effect of Potenlini(Glycyrrhizic Acid) and Salviae Miltiorrhizae for Antifibrosis

本研究选择７２ 例慢性乙型肝炎（ＣＨＢ） 病人，分强力宁加丹参组、强力宁组、丹参组及对照组。治疗前后检测肝功能、病毒指标及肝纤维化血清学指标（ＨＡ、ＰＣⅢ，ＬＮ 及ＩＶ－ Ｃ） 。结果表明，治疗后肝纤维化指标均有不同程度好转，各治疗组与治疗前及对照组治疗后比较差异显著，且强力宁与丹参联用抗肝纤维化作用优于单用强力宁或丹参。

Thisstudy enrolled 72 patients with chronic hepatitis B(CHB) accordingtothe diagnos ticcriteria-They were divided into four grops:potenlini and salviae miltiorrhizae (SM) grop (20 pa tients) ;potenlini group (18 patients) ;SMgroup (19 patients) and the control group (15 patients)-The liverfunction were provedin all groups,The serum parameters offibrosis allsignificantly changed after two orthreetreatment duration in treated groups-The results showed that potenlini and SM both had the effectofantifibrosisand the combination ofthem can promoto the effect ofantifibrosis-