摘要
[目的]探讨原发性乳腺恶性淋巴瘤的诊断要点,以及肿瘤切除的相关问题和术后的辅助治疗。[方法]对1970年至1993年2月诊治的12例原发性乳腺恶性淋巴瘤患者进行随访分析。[结果]经过6年4个月的中位随访期,5年总生存率为50%。[结论]原发性乳腺恶性淋巴瘤临床诊断较难。肿块多生长迅速,但对皮肤、肌肉、腋淋巴结浸润少,无需选择根治手术。对肿瘤<5cm者可行肿块切除术,>5cm者行乳腺切除手术,腋窝淋巴结有肿大者可加做腋窝淋巴结清扫。术后早期化疗可有效延长患者的生存年限。
Purpose]To diagnosis diagnosis and treatment for primary breast malignant lymphoma.[Methods]Tweleve cases with primary breast malignant lymphoma were treated from 1970 to February 1993.All the cases were followed-up and analyzed.[Results]Median followed - up period was 76 months.The 5 - year survival rate was 50.0%.[Conclusion]The primary breast malignant lymphoma grows rapidly,but less invision to skin, muscle and axillary lymph node.Radical mastectomy might not be necessary.Wide local excision was adopted in the treatment of those patients with tumor less than 5cm in diameter.Simple mastectomy should be performed for tumor more than 5cm in diameter.Axillary nodes dissection should be added to enlarged axillary node.Early postoperative chemotherapy may improve patient's survival.