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视黄醇结合蛋白4与冠心病的关系 被引量：4

Relationship between Retinol-Binding Protein 4 and Coronary Heart Disease
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摘要 目的研究视黄醇结合蛋白4(RPB4)与冠心病(CHD)之间的关系。方法研究对象78例,分为两组:正常对照组和冠心病组。测定血浆RPB4水平,采集有关数据。结果冠心病组血浆RPB4水平明显高于正常对照组[(44.72±16.98),(39.60±12.10),P<0.05]。相关分析显示血浆RBP4与腰围、腰臀比、BMI、TC、ln(TG)、FINS、FCP、ln(HOMA-IR)呈正相关。多元逐步回归分析,ln(TG)是血浆RBP4独立相关因素。结论血浆RBP4在冠心病的发病过程中起一定作用。 Objective To investigate the relationship between the plasmal retinol-binding protein 4（RBP4）levels and coronary heart disease（CHD）.Methods Totally 78 subjects were divided into two groups：controls（n=47）and patients with CHD（n=31）,Plasmal RBP4 levels were measured by ELISA.Results Plasmal RBP4 levels in patients with CHD were significantly higher than that of controls.Plasmal RBP4 level was positively correlated with Waist,WHR,BMI,TC,ln（TG）,FINS,FCP and ln（HOMA-IR）.In a multiple stepwise regression analysis,ln（TG） was independent variable of RBP4.Conclusion Elevated RBP4 levels might affect the development of CHD.
作者 高璐 常志文 秦明照 陈晓燕
机构地区 首都医科大学附属北京同仁医院干部医疗科
出处 《医药论坛杂志》 2010年第15期10-12,共3页 Journal of Medical Forum
关键词 视黄醇结合蛋白4 冠状动脉疾病 相关性分析 Retinol-binding protein 4 Coronary disease Relation analysis
分类号 R541.4 [医药卫生—心血管疾病]
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参考文献10

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共引文献26

同被引文献42

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医药论坛杂志
2010年 第15期

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