缺血性中风病急性期证候变化规律研究

Research of TCM syndrome variation regularity in acute stage of ischemia stroke

目的:探讨缺血性中风病急性期证候变化规律研究。方法:采用前瞻性临床调查的方法,对发病72h内入院患者进行自入院当天至发病第14d的连续动态采集临床信息,研究缺血性中风病急性期的证候变化规律。结果:缺血性中风急性期以风、火、痰3证出现频率最多,并呈现不同变化规律;6个基本证候出现了44种组合形式,风证和火痰证出现频次随病程的延长而增加;风痰证在发病3d后出现频次减少;风火证在第3d出现频次最多;痰证出现频次在第5d后开始下降;风火痰证出现频次在第5d出现频次最多,且波动较为明显;风痰瘀证在前3天出现频次较多。结论:缺血性中风病急性期起病迅速,变化多端,具有证候变化复杂的特性;反映出《中风病辨证诊断标准》在临床应用中的适用范围受时间因素的影响,提示完善"中风病辨证诊断标准"的必要性和迫切性。

Objective：To explore TCM syndrome variation regularity on acute stage of ischemia stroke.Methods：To collect clinical dynamic state information of ischemia stroke from 72h to 14days by using prospective clinical research method and investigate TCM syndrome variation regularity in acute stage of ischemia stroke.Results：Wind,fire and phlegm syndromes were the most frequent syndromes in acute stage of ischemia stroke.They appeared varied regularity.There were forty-four combination patterns about six basic syndromes.The wind syndrome and fire-phlegm syndrome were increasing in acute stage of ischemia stroke.The wind-phlegm syndrome was decreasing in the first three days,the wind-fire syndrome peaked on the third day,the phlegm was decreasing on the fifth day.The wind-fire-phlegm was the most frequent and undulate syndrome on the fifth day.The wind-phlegm-stagnation syndrome was increasing for the first three days.Conclusion：There were fastly morbility,changeable and complicated syndrome change in acute stage of ischemia stroke.It was very necessity and urgency for complementing diagnostic criteria of stroke differentiation.