FoxM1在衰老与肿瘤发生中的意义
摘要
FoxM1是fox转录因子家族中的一员,广泛存在于具有分裂活性的细胞中。FoxM1是经典的增殖相关因子,其表达与细胞周期密切相关。FoxM1与组织器官发育及细胞分化增殖紧密相关。FoxM1缺失是导致衰老的重要原因。在许多肿瘤的发生中,FoxM1表达增高。
出处
《国际检验医学杂志》
CAS
2010年第8期852-854,共3页
International Journal of Laboratory Medicine
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