强化降糖治疗对2型糖尿病患者生存质量及血糖的影响研究

Effects of intensive blood glucose control on quality of life and blood glucose in patients with type 2 diabetes

目的:探讨强化降糖治疗对2型糖尿病(T2DM)患者生存质量及血糖的影响。方法:将120例T2DM患者随机分为观察组和对照组。对照组按照《中国糖尿病防治指南》给予标准降糖治疗,治疗组给予强化降糖治疗。两组患者在治疗前和随访3年后分别进行生存质量评价和血糖指标测查。结果:治疗后,治疗组生存质量各维度评分及总分与治疗前和对照组比较显著下降(P<0.05),对照组治疗前后生存质量各维度评分及总分差异无统计学意义(P>0.05);两组治疗后血糖水平均明显降低,与治疗前比较有显著性差异(P<0.05),且治疗组与对照组比较显著降低(P<0.05)。结论:采用强化降糖治疗,可以达到血糖的理想控制,提高患者的生存质量。

Objective： To investigate the effect of intensive blood glucose control on quality of life （QOL） and blood glucose in patients with type 2 diabetes （T2DM）. Methods： 120 cases of patients with type 2 diabetes were randomly divided into treatment group and control group. The control group was given standard glucose treatment accordance with the ＂Guide to Diabetes Control＂, the treatment group was given intensive blood glucose treatment. The patients of two groups before and after follow-up after 3 years were observed QOL and blood glucose. Results： After treatment, the dimensions of QOL scores and total scores of the treatment group were significantly decreased ,（P 〈0.05）, before and after treatment the dimensions of QOL scores and total scores of the control group were no statistically significant （ P〉 0.05）; After treatment, the blood glucose of the two groups reduced, compared with before treatment the difference was significant （P 〈0.05）, and the treatment group compared with the control group reduced significantly （P 〈0.05）. Conclusion： The intensive blood glucose can effectively control the blood glucose level and improve the QOL in patients with type 2 diabetes.