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脑缺血后神经发生 被引量:3

Neurogenesis after cerebral ischemia
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摘要 脑缺血后神经发生是神经科学领域的研究热点之一。文章主要从脑缺血后神经发生的主要过程、调节因子、信号通路、微环境以及如何促进脑缺血后神经发生等方面阐述神经发生的研究进展,旨在为卒中后神经功能恢复提供新的治疗思路。 The neurogenesis after cerebral ischemia is one of the research hotspots in the field of neuroscience.This article mainly expounds the advances in research on neurogenesis from the main processes,regulatory factors,signal pathways and microenvironment as well as how to promote neurogenesis following cerebral ischemia.Our purpose is to provide new treatment ideas for the recovery of neurological function following stoke.
出处 《国际脑血管病杂志》 北大核心 2010年第7期537-542,共6页 International Journal of Cerebrovascular Diseases
基金 国家自然科学基金(30570626,30870855) 北京市自然科学基金(7082028)
关键词 神经发生 脑缺血 新生血管化 病理性 干细胞 神经元 Brain ischemia Neurogenesis Neovascularization,pathologic Stem cells Neurons
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参考文献37

  • 1Liu C,Zhao X.MicroRNAs in adult and embryonic neurogenesis.Neuromolecular Med,2009,11:141 -152.
  • 2Altman J.Are new neurons formed in the brains of adult mammals?Science,1962,135:1127-1128.
  • 3Goldman SA,Nottebohm F.Neuronal production,migration,and differentiation in a vocal control nucleus of the adult female canary brain.Proc Natl Acad Sci USA,1983,80:2390-2394.
  • 4Whitman MC,Greer CA.Adult neurogenesis and the olfactory system.Prog Neurobiol,2009,89:162-175.
  • 5Zhang RL,Zhang ZG,Chopp M.Ischemic stroke and neurogenesis in the subventricular zone.Neuropharmacology,2008,55:345-352.
  • 6Colucci-D'Amato L,di Porzio U.Neurogenesis in adult CNS:from denial to opportunities and challenges for therapy.Bioessays,2008,30:135-145.
  • 7Okano H,Sakaguchi M,Ohki K,et al.Regeneration of the central nervous system using endogenous repair mechanisms.J Neurochem,2007,102:1459-1465.
  • 8Salazar-Colocho P,Lanciego JL,Del Rio J,et al.Ischemia induces cell proliferation and neurogenesis in the gerbil hippocampus in response to neuronal death.Neurosci Res,2008,61:27-37.
  • 9Carmichael ST.Themes and strategies for studying the biology of stroke recovery in the poststroke epoch.Stroke,2008,39:1380-1388.
  • 10Burns TC,Verfaillie CM,Low WC.Stem cells for ischemic brain injury:a critical review.J Comp Neurol,2009,515:125-144.

二级参考文献24

  • 1Shimokawa H, Takeshita A. Rho-Kinase is an Important Thera peutic Target in Cardiovascular Medicine[J]. Arterioseler Thromb Vasc Biol(S1079-5642),2005,25,1767-1775.
  • 2Budzyn K, Marley PD, Sobey CG. Targeting Rho and Rho-kinase in the Treatment of Cardiovascular Disease[J]. Trends Pharmacol Sci(S0165-6147) ,2006,27:97- 104.
  • 3Iwasaki H, Okamoto R, Kato S, et al. High Glucose Induces Plasminogen Activator Inhibitor 1 Expression Through Rho/ Rho-kinase-mediated NF-kappaB Activation in Bovine Aortic Endothelial Cells[J]. Atherosclerosis(S0021 9150), 2008, 196(1) :22-28.
  • 4Chrissobolis S, Budzyn K, Marley PD, et al. Evidence that Estrogen Suppresses Rho-kinase Function in the Cerebral Circulation in Vivo[J]. Stroke(0039-2499), 2004,35:2200-2205.
  • 5Obara K o Nishizawa S, Koide M, et al. Interactive Role of Protein Kinase C delta with Rho kinase in the Development of Cerebral Vasospasm in a Canine Two-hemorrhage Model[J]. J Vasc Res(SlO18-1172),2005,42:67-76.
  • 6Watanabe Y. Faraci FM, Heistad DD. Activation of Rho-associated Kinase During Augmented Contraction of the Basilar Artery to Serotonin after Subarachnoid Hemorrhage[J]. Am J Physiol Heart Circ Physio[(S0363-6135),2005,288: H2653-2658.
  • 7Wickman G, Lan C, Vollrath B. Functional Roles of the Rho/ rho Kinase Pathway and Protein Kinase C in the Regulation of Cerebrovascular Constriction Mediated by Hemoglobin: Rele vance to Subarachnoid Hemorrhage and Vasospasm[J]. Cire Res(S0009-7330), 2003,92:809-816.
  • 8Zhao J. Zhou D, Guo J, et al. Effect of Fasudil Hydrochlo ride, a Protein Kinase Inhibitor, on cerebral Vasospasm And Delayed Cerebral Ischemic Symptoms after Aneurysmal Subarachnoid Hemorrhage [J]. Neurol Med Chit (Tokyo) (S0470-8105),2006,46(9) :421-428.
  • 9Iwabuchi S, Yokouchi T, Hayashi M, et al. Intra-arterial Administration of Fasudil Hydrochloride for Vasospasm Following Subarachnoid Hemorrhage-analysis of Time-density Curve with Digital Subtraction Angiography [J]. Neurol Med Chit (S0470-8105) ,2006,46(11) :535-539.
  • 10Suzuki Y, Shibuya M, Satoh S, et al. A Postmarketing Surveillance Study of Fasudil Treatment after Aneurysmal Subarachnoid Hemorrhage[J]. Surg Neurol(S0090-3019), 2007, 68(2) :126- 131.

共引文献5

同被引文献54

  • 1王建玲,吴露,张伟,邓常青.三七总皂苷对大鼠主动脉球囊损伤后血管内膜增生及PCNA表达的影响[J].中国中药杂志,2009,34(6):735-739. 被引量:5
  • 2李慧敏,林迤逦,杨华姿.针刺对脑性瘫痪患儿独立步行能力的改善作用(英文)[J].中国临床康复,2004,8(33):7603-7605. 被引量:1
  • 3张谦,潘晓东,皮敏,于海波.益肾通督针法结合现代康复治疗小儿脑瘫26例临床观察[J].中国中医药科技,2006,13(4):271-272. 被引量:3
  • 4Li J J, Wu L H, Cao Q,et al. Endothelins-1/3 andendothelin-A/B receptors expressing glial cells withspecial reference to activated microglia in experimentallyinduced cerebral ischemia in the adult rats [ J ].Neuroscience, 2010 ,167(3) :665.
  • 5Hui Q, Chen Z,Zhi-bin S, et al. Protective effects andmechanism of Panax Notoginseng saponins on oxidativestress-induced damage and apoptosis of rabbit bonemarrow stromal cells [ J ]. Journal of Chinese IntegrativeMedicine. 2010,16(6) ,525.
  • 6ie-wen G J, i-ming L I, Guang-qing Q, et al. Effects ofpanax notoginseng saponions on ACE2 and TNF-alpha inrats with post-myocardial infarction-ventricularremodeling[ J]. Journal of Chinese Medicinal Materials,2009,33(1) ;89.
  • 7Li H, Deng C, Chen B, et al. Total saponins of panaxNotoginseng modulate the expression of caspases and at-tenuate apoptosis in rats following focal cerebral ischemi-a-reperfusion [ J] . Journal of Ethnopharmacology, 2009 ,121(3) :412.
  • 8Liu W J, Tang H T, Jia Y T, et al. Notoginsenoside R1attenuates renal ischemia-reperfusion injury in rats[ J].Shock, 2010,34(3) :314.
  • 9LIU Y,ZHANG H G, JIA Y, et al. Saponinaccumulation in the seedling root of Panax notoginseng[J]. Biol Pharm Bull, 2010,33(8) :1324.
  • 10Li Q, Zhang R,Ge Y 1,et al. Effects of neuregulin onexpression of MMP-9 and NSE in brain of oschemia/reperfusion rat[ J]. Journal of Molecular Neuroscience,2009,38(2) :207.

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