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Th17细胞与桥本氏甲状腺炎

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摘要 Th17细胞是新发现的一种与Th1和Th2细胞亚群不同的新型辅助性T细胞亚群，该类细胞是由天然T细胞前体分化而来，具有独立分化和发育调节机制，并主要产生白介素17效应因子，在自身免疫性疾病中发挥重要调节作用。桥本氏甲状腺炎是一种器官特异性自身免疫病，Th17细胞因子在其发病中亦起着重要作用。本文仅就Th17细胞的诱导产生、发育机制及其细胞因子在桥本氏甲状腺炎中的研究进展做一综述。
作者 陈万志 余济春
机构地区 南昌大学研究生院医学部 南昌大学第一附属医院耳鼻咽喉头颈外科
出处 《国际耳鼻咽喉头颈外科杂志》 2010年第5期280-284,共5页 International Journal of Otolaryngology-Head and Neck Surgery
关键词 T淋巴细胞(T-Lymphocytes) 桥本病(Hashimoto Disease)
分类号 R5 [医药卫生—内科学]
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参考文献20

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二级参考文献18

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国际耳鼻咽喉头颈外科杂志
2010年 第5期

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