摘要
目的探讨米力农治疗急性心肌梗死后心力衰竭的效果与安全性.方法 28例急性心肌梗死后出现心力衰竭的患者入院后接受米力农(剂量为0.375～0.75mg/(kg.d)治疗2～4d,治疗前后利用彩色多普勒心脏超声诊断仪评估患者的心功能.结果米力农治疗后患者的心指数和射血分数显著增加,分别为(2.3±0.5)vs(2.7±0.6)L/(min.m2)和(35±6)%vs(43±4)%,P<0.05,未观察到严重的副反应的发生.结论米力农能有效地治疗急性心肌梗死后心力衰竭。
Objective To investigate the therapeutic effect and safety of milrinone in treatment of acute myocardial infarction（AM）I patients with severe heart failure.Methods Twenty-eight AMI patients with severe heart failure received intravenous milrinone therapy for 2～4 days [0.375～0.75 mg/（kg.d）].All patients＇ cardiac function was measured by echocardiography before and after the therapy.Results Compared with baseline values,the cardiac index and ejection fraction were significantly increased from 2.3±0.5 to 2.7±0.6L/（min.m2）（P〈0.05） and 35±6 to 43±4%（P〈0.05） respectively after milrinone therapy.No any severe side effects were observed.Conclusion Milrinone is effective and safe in treatment of AMI patients with severe heart failure.
出处
《昆明医学院学报》
2010年第8期124-126,共3页
Journal of Kunming Medical College
关键词
米力农
急性心肌梗死
心力衰竭
Milrinone
Acute myocardial infarction
Heart failure
