2型糖尿病对急性脑梗死患者脑干听觉诱发电位及预后的影响

Effect of typeⅡ diabetes mellitus on brainstem auditory evoked potential and prognosis in patients with acute cerebral infraction

目的探讨2型糖尿病对急性脑梗死患者脑干听觉诱发电位(BAEP)及神经功能的影响。方法选择急性期脑梗死患者154例,包括2型糖尿病合并脑梗死患者(DMCI)74例和非糖尿病脑梗死患者(NDMCI)80例,全部患者发病72h内均行BAEP检查和美国国立卫生院卒中量表(NIHSS)评分。结果 DMCI组与NDMCI组患者BAEP异常率分别为81.2%和63.8%,差异有统计学意义(P<0.05);DMCI组患者BAEP主波潜伏期和波间期均较NDMCI组患者明显延长(P<0.05);2组患者BAEP异常率与NIHSS评分呈正相关。结论 2型糖尿病加重急性期脑梗死患者脑干功能损伤,BAEP可作为急性期脑梗死患者预后的有效评估指标。

Objective To study the effect of typeⅡ diabetes mellitus on brainstem auditory evoked potential and neurologic function in patients with acute cerebral infraction.Methods One hundred and fifty-four patients with acute cerebral infraction who had history of diabetes were divided into two group（DMCI group and NDMCI group）.DMCI group included 74 patients with typeⅡ diabetes mellitus.BAEP and NIHSS were performed in 72 hours after onset.Results The abnormality rate of BAEP in DMCI group was 81.2% and that in NDMCI group was 63.8 %.The peak latency and inter peak latency in DMCI group were apparently prolonged as compared with those in NDMCI group（P〈0.05）.The abnormality rate in patients with cerebral infraction had a positive correlation with the mean score of NIHSS.Conclusions Diabetes mellitus may enhance the damage to the function of brainstem in patients with acute cerebral infraction.BAEP may be used as a useful reference index of prognosis in patients with acute cerebral infraction.