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NK细胞与异种移植 被引量：2

Natural killer cells in xenotransplantation
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摘要 异种移植是解决供体器官短缺的最有前景的途径之一,但异种移植后发生的强烈的免疫排斥反应限制了它的临床应用。相比同种移植,非特异性免疫系统在异种移植中发挥更重要的作用。NK细胞作为非特异性免疫系统的重要组成部分,通过多种机制参与对异种移植物的免疫排斥。 Xenotransplantation is one of the most promising solutions to the shortage of human donors,but severe immunological rejection after transplantation denies the clinic application.The nonspecific immune system plays a more important role in xenotransplantation compared with allotransplantation.And NK cells,which is an important component of the nonspecific immune system,carries out the xenorejection of xenograft by lots of mechanisms.
作者 高威 沈振亚
机构地区 苏州大学附属第一医院心血管外科
出处 《免疫学杂志》 CAS CSCD 北大核心 2010年第8期727-729,共3页 Immunological Journal
关键词 异种移植 NK细胞 免疫排斥 Xenotransplantation NK cells Immunological rejection
分类号 R392.4 [医药卫生—免疫学]
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参考文献21

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同被引文献22

  • 1Boyton R J, Altmann DM. Natural killer cells, killer immunoglobulin-like receptors and human leucocyte antigen class I in disease[J]. Clin Exp Immunok 2007, 149(1):1-8.
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免疫学杂志
2010年 第8期

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