慢性乙型肝炎青紫舌的形成机制及临床意义

Blue or purple tongue in patients with chronic hepatitis B: mechanisms and clinical significance

目的:研究慢性乙型肝炎青紫舌的分布规律,以及青紫舌与年龄、性别、病情、证素、微循环的关系.方法:选择2002-12/2003-09首都医科大学附属北京佑安医院就诊的慢性乙型肝炎患者113例,进行舌色分布,中医证素,病情等调查,检测甲襞微循环情况,应用SPSS11.5统计软件进行分析.结果:青紫舌是慢性乙型肝炎的主要舌色表现.该舌色与病情程度(r=0.293,P=0.013)、湿证素(r=-0.251,P=0.023)、血瘀证素(r=-0.226,P=0.043)、年龄等相关,其形成机制与微循环障碍有关.结论:青紫舌对于慢性乙型肝炎临床辨证具有重要的指导意义.

AIM： To examine the distribution of blue or purple tongue in patients with chronic hepatitis B by analyzing the relationship of blue or purple tongue with age, gender, state of the illness, syndrome elements, and microcirculation.METHODS： A total of 113 patients with chronic hepatitis B were investigated for tongue color, syndrome elements of Chinese medicine, state of the illness, and nail microcirculation. RESULTS： Blue or purple is the main tongue color in patients with chronic hepatitis B. The development of blue or purple tongue is highly correlated with state of the illness （r = 0.293, P = 0.013）, dampheat syndrome element （r = -0.251, P = 0.023）, blood stasis （r = -0.226, P = 0.043） and patients’ age. Microcirculatory disturbance may be responsible for the formation of blue or purple tongue in patients with chronic hepatitis B. CONCLUSION： The development of blue or purple tongue may provide a guide to syndrome differentiation in patients with chronic hepatitis B.