重症手足口病31例临床分析

Clinical analysis of 31 cases with Hand-foot -mouth disease

目的分析手足口病重症病例的临床特点，以助于提高对该病的早期识别。方法对31例重症手足口病患儿临床资料进行回顾性分析。结果31例重症手足口病患儿，3岁以内占96．8％，前3d重症发生率90．3％；发热及皮疹100％，不典型皮疹35．5％；呕吐71．0％；精神差74．2％，嗜睡61．3％，易激惹41．9％，肌阵挛64．5％，心率异常61．3％，呼吸异常32．3％，血压异常19．4％；合并神经系统症状83．9％，后遗症12．9％，死亡9．7％。结论重症手足口病以神经系统并发症为主，6个月-2岁多见；精神差、嗜睡、呕吐症状突出，不典型皮疹多见；呼吸、心率、血压异常是手足口病极重症的信号，而广蜜高．

Objective To analyse the clinical features of the severe hand-foot-mouth disease（ HFMD）, in order to identify the early incidence of the HFMD. Methods Retrospectively analyzed clinical data of 31 severe children cases of HFMD. Results 31 cases of children with severe HFMD, under 3 years old accounted for 96. 8%of all;90. 3%of the severe cases were found in the first 3 days of the onsets; All the severe cases were with fever and eruption, atypical rash 35.5 % ; vomiting 71% ; bad spirit 74. 2% ; drowsiness 61.3 %, Irritability 41.9%, muscular Paroxysmal Spasm 64. 5% ;Abnormal heart rate 61.3%, abnormal breathing 32. 3%, abnormal blood pressure 19.4% ;83.9% with the nervous symptoms, 12. 9% with the sequelae, and the mortality was 9. 7%. Conclusion Severe HFMD were often occurred at the age of 6 months to 2-year-old children, neu- rological complications were the main clinical manifestasions. Poor spirit, drowsiness, vomiting were the prominent symptoms. Atypical rashes were often found. It＇ s the severe signal of HFMD that abnormality of breathing, heart rate and blood pressure. The mortality was high.