经气管注入巴曲亭治疗气管切开术后出血的临床观察

Clinical observation on application of hemocoagulase atrox for injection to hemorrhage after tracheotomy by trachea

目的观察气管内注入巴曲亭治疗气管切开术后的出血。方法 36例ICU病房气管切开术后气道内出血患者随机分为3组:经气管内注入巴曲亭治疗组、静脉注射巴曲亭治疗组及经气管内注入去甲肾上腺素治疗组。观察其对患者的止血效果及治疗前后的血小板计数及凝血功能的变化。结果 3组患者治疗前后血小板计数及凝血功能差异无统计学意义,经气管注入巴曲亭组的止血效果明显好于气管内注入去甲肾上腺素组和静脉注射巴曲亭组。结论气管内注入巴曲亭对治疗气管切开后气管内出血有明显的抑制作用,且给药方便,疗效迅速直接。

Objective To determine the therapeutic effect and feasibility of hemocoagulase atrox for injection to bleeding after tracheotomy by trachea.Methods Forty-five patients who all had trachea bleeding were randomly divided into 3 groups：group in hemocoagulase atrox for injection by trachea（n=12）,group in hemocoagulase atrox for injection by vein and nonadrenalin group（n=12）.The hemostatie effect,the platelet and changes of blood coagulation were observed.Results The counts of platelet and function of blood coagulation showed no obvious changes before and after the therapy in the three groups,the hemostatic effect of hemocoagulase atrox for injection by the trachea group was evidently better than that of hemocoagulase atrox for injection by the vein group and noradrenalin group.Conclusion It is safe and available to apply hemocoagulase atrox for injection to bleeding after tracheotomy by trachea.