双侧同时肺癌4例报告及文献复习

Four cases report of synchronous bilateral multiple lung cancers and review of the literature

目的探讨双侧同时多发性肺癌的临床特点、诊断、病理、治疗及预后。方法对4例双侧同时多发性肺癌的临床资料进行回顾性分析,并结合文献对其临床进行分析。结果 4例双侧肺癌均为重度吸烟者,以咳嗽伴痰中带血为主,影像学以中央型肺癌及阻塞性肺炎为主,纤支镜下均见双侧支气管内的新生物,病理学主要为鳞癌,对治疗的反应及预后与一般中央型肺癌相似。结论双侧同时多发性肺癌临床少见,临床表现与一般中央型肺癌相似,惟纤支镜下见双侧支气管内的新生物。

Objective To explore the clinical characteristics,diagnosis,pathology,treatment and prognosis of synchronous bilateral multiple lung cancers.Methods With four cases reported and related literature reviewed,the clinical characteristics,pathology,diagnosis,treatment,and prognosis of synchronous bilateral multiple lung cancers were described.Results All of four patients were heavy smokers.The main symptoms of synchronous bilateral multiple lung cancers were productive cough with bloody sputum.Central type lung cancer and obstructive pneumonia were showed in chest CT,and neoplasm in both sides of bronchial tree was found under bronchofiberscope,squamous cell carcinoma was the main pathological type.The treatment response and prognosis of SBMLC had no significant difference with common central type lung cancer.Conclusion SMBLC in clinic is rare,the clinical manifestation of SMBLC is similar to the clinical manifestation of central type lung cancer.The only difference between them is neoplasm in both sides of bronchi under bronchofiberscope.