高血压左室肥厚与肥厚性心肌病心肌声学密度的比较

Comparison of the myocardial echodensity between hypertensive left ventricular hypertrophy and hypertrophic cardiomyopathy

旨在通过采用计算机辅助的声学组织密度定量技术分别对高血压在室肥厚（LVH）及肥厚性心肌病（HCM）患者的心肌组织欢阶特征进行分析，以期评价该方法鉴别不同病因心肌肥厚的可行性。材料和方法：研究对象为32例正常人，28例LVH的高血压病人和35例HCM患者。常现获取二尖瓣和乳头肌水平的短轴切面。采用WindoW95支持下的PhotoShop3．仍软件对图像进行分析。结果：HCM患者肥厚的室间隔、前壁、侧壁与后壁的灰阶均值比、离散度比均明显高于正常（P＜0．05），而高血压LVH者相应节段的比值（除二尖瓣水平室间隔的灰阶离散度比外）仍在正常范围（P＜0．05），且比较HCM与高血压LVH的均值比。离散度比，除二尖瓣水平室间隔的灰阶离散度比外差别有统计学意义（P＜0．05）。结论：声学组织密度定量技术有助于鉴别高血压LVH与HCM的不同心肌组织特征。

Objective: To evaluate the feasibility of cardiac tissue characterization to distinguish the distinct ventricular hypertrophy, we compared the gray - scale of paients with hypertensive left ventricular hypethephy(LVH) and those with hypertrophic cardiomyopathy(HCM) with computer - assistant quantitative analysis of myocardial echodensity. Materials and Methods: Thirty - two normal subjects,twenty - eight paients with concentric hypertensive LVH and thirty - five with HCM were selected.The left ventricular short - axis viewswere collected M at the papillary level and at the mitral level, and the gray - scale of myocardium at the interventricular septum, anteriorwall, lateral wall and posterior wall was analyzed by Adobe Photoshop 3. 05 software. Results: The mean gray - seale ratio and the Standarddeviation(SD) ratio of interventricular septum, anterior wall and lateral wall in the patients with HCM were not only higher at the papillarylevel(P < 0.05), but also at the mitral level(P < 0. 05). The significant difference was also exist between HCM and hypertensive LVH(except SD ratio of the interventricular septum at the mitra level) (P < 0. 05); whereas there was no difference between hypertensive patientsand normals(except SD ratio of the interventricular septum at the mitral level) (P > 0. 05). Conclusion: Quantitative analysis of myocardialechodensity was helpful in differential the distinct tissue characterization between hypertensive LVH and HCM.