口腔颌面部淋巴管畸形110例临床分析

Clinical data of oral and maxillofacial lymphatic malformations(report of 110 cases)

目的探讨口腔颌面部淋巴管畸形的临床特征与治疗方法,为临床积累经验,提高治疗效果。方法回顾性分析新疆医科大学第一附属医院口腔颌面外科2003年1月～2007年12月收治的110例口腔颌面部淋巴管畸形患者的临床资料。结果口腔颌面部淋巴管畸形共110例,男女性别之比为1.34∶1。发病年龄<1岁者为64例,占58.18%,<2岁者为76例,占69.09%。发生的部位依次为舌部(40.00%)、唇颊部(18.18%)、颈部(12.73%)及下颌下区、腮腺区。组织分型为微囊型72例,大囊型38例。手术治疗84例,占76.36%,平阳霉素局部注射13例,占11.82%,20%高渗盐水局部注射8例,占7.27%,手术+平阳霉素局部注射5例,占4.55%。结论口腔颌面部淋巴管畸形中,男性多于女性,小儿多见,好发部位依次为舌、唇颊部、颈部等。组织学分型以微囊型多见,大囊型相对少。手术切除、平阳霉素局部注射是治疗口腔颌面部淋巴管畸形的理想和有效手段。

Objective To explore the clinical feature and treatment ways of oral and maxillofacial lymphatic malformation.Methods The clinical data of 110 patients with oral and maxillofacial lymphatic malformation treated from December 2002 to December 2007 in department of oral and maxillofacial surgery.The First Affiliated hospital of Xinjiang Medical University,was retrospectively analyzed.Results Among 110 cases,the ratio of male to female was 1∶0.74.Oral maxillofacial lymphatic malformation occurred more often in children under 2 years old.The most common locations of maxillofacial lymphatic malformation were tongue（40.00%）,labial and buccal division（19.18%）,neck region（12.73%）,submaxillary region,parotid region etc.There were 110 case with pathologic diagnosis,including 70 cases of microcapsule type.84 cases（76.36%）were operated,13 cases（11.82%）were injected Pingyangmycin,8 cases（7.27%）were through injecting 20% Sodium.5 cases（4.55%）were cured through surgery and Pingyangmycin.Conclusion The oral and maxillofacial maxillofacial lymphatic malformation are common in child phase and male was more than female.The most common locations of oral and maxillofacial lymphatic malformation were tongue,labial and buccal division,neck region,submaxillary region etc.Surgical therapy and Pingyangmycin are the main way to treat oral and maxillofacial lymphatic malformation.So as to gain the better result.