嗜酸细胞性胃肠炎7例临床分析

Clinical study of eosinophilic gastroenteritis(report of 7 cases)

目的探讨嗜酸细胞性胃肠炎(Eosinophilic gastroenteritis,EG)的临床特点、诊断、治疗及其误诊原因。方法 7例患者中有5例根据患者的病史、临床表现、实验室检查、多次内镜检查确诊为EG并用激素治疗,另2例术前诊断为瘢痕性幽门梗阻行胃大部切除术后病理诊断为EG,术后用激素治疗。结果 7例患者均痊愈出院,其中1例术后发生胃排空障碍、吻合口溃疡,经保守治疗痊愈。结论 EG临床表现无特异性,内镜表现多为黏膜片状糜烂和水肿,内镜应行多点活检,激素疗效好,对肌层病变型伴有幽门梗阻患者可以手术治疗。

Objective To investigate clinical characteristic,diagnosis and treatment of eosinophilic gastroenteritis（EG）,and analyze the causes of misdiagnosis.Methods Five patients were diagnosed as EG with their case history,clinical manifestations,laboratory tests and many times endoscopies examination and hormonal therapy.Preoperative diagnosis of the other 2 cases were cicatricial pyloric obstruction and were operated with subtotal gastrectomy.The pathological diagnosis of these 2 cases was EG.They were used hormonal therapy after operation.Results Seven patients were fully recover from EG and 1 case occurrenced gastric emptying disorder and marginal ulcer and recoveried with expectant treatment.Conclusion Clinical presentations of EG are not specific.Endoscopy showed erosion and edema.Endoscopic should do multiple punch biopsy.The consequence hormonal therapy of EG is good.The muscular type of EG with pyloric obstruction can do surgical operation.