小儿肺炎134例痰培养及药物敏感试验结果分析

Analysis of sputum culture and drug sensitivity tests in 134 cases of children with pneumonia

目的为了了解小儿肺炎病原菌的感染情况,进一步给临床治疗用药提供依据。方法对新入院或治疗效果不佳且诊断为肺炎的患儿进行深部取痰送检并进行药物敏感试验,然后进行统计学分析。结果共培养出致病菌134株,其中克雷伯菌属34株(肺炎克雷伯杆菌24株)、阴沟肠杆菌12株、大肠埃希菌30株、真菌16株,其他42株。结论本地区引起肺部感染的病原菌主要为革兰阴性菌,而革兰阳性菌较少,其中克雷伯菌属占有较大比重,对常用的青霉素类、头孢类的敏感程度在逐渐降低,而对少用或不用的抗生素的敏感程度较高。因此,尽早做痰培养及药物敏感试验,尽早应用敏感抗生素进行治疗就显得非常重要。

Objective In order to understand the infection situation of pneumonia pathogens in children for providing the basis for the clinical use of drugs.Methods Sputum culture and drug sensitivity tests were conducted for children diagnosed as pneumonia,and then the results were analyzed statistically.Results 134 pathogenic bacteria were isolated from specimens,including 34 strains of Klebsiella （24 strains of Klebsiella pneumoniae）,12 strains of Enterobacter cloacae,30 strains of Escherichia coli,16 strains of Fungi and 42 strains of other pathogenic bacteria.Conclusion Main pathogenic bacterium in this ares is Gram-negative bacteria,in which Klebsiella is in the majority.The sensitivity of Penicilliins and Cephalosporins in pneumonia pathogens has decreased gradually.Therefore,sputum culture and drug sensitivity tests should be conducted as soon as possible,and the application of sensitive antibiotics is very important.