摘要
EV71引起的手足口病(HFMD)已经严重威胁婴幼儿的健康,但目前仍无特效抗病毒药物问世。许多科技工作者正在研发各种类型的EV71疫苗,包括灭活疫苗、类病毒颗粒疫苗、合成肽疫苗、DNA疫苗及转基因口服疫苗。本文就EV71疫苗的研究进展做一简要综述并对各自优劣和发展前景进行讨论。
EV71 infection has become a serious public health threat especially among young children.Yet,at present,no specific antiviral drug against EV71 infection is available.A number of scientists are studying various kinds of vaccines,including inactivated vaccine,virus-like particle vaccine,DNA vaccine, synthetic peptide vaccines,and transgenic oral vaccine.This article reviews the recent advancement in the design of various kinds of vaccine against EV71 as well as their prospective usefulness,effectiveness,weakness and developments in the foreground.
出处
《生物医学工程学杂志》
EI
CAS
CSCD
北大核心
2010年第4期933-936,共4页
Journal of Biomedical Engineering
基金
国家自然科学基金资助项目(30400402
30571708)
国家科技支撑计划资助项目(2006BAI03B12)
关键词
手足口病
EV71
疫苗
Hand-foot-mouth disease（HFMD）
Enterovirus 71（EV71）
Vaccine
