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肾小球疾病的免疫作用机制研究进展 被引量:1

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摘要 传统认为,肾小球肾炎(glomerulonephritis,GN)的发病机制与肾小球原位免疫复合物形成或循环中免疫复合物沉积于肾脏,激活补体而引起的肾脏损伤等有关.近年研究发现,GN的发病机制,不仅与T、B淋巴细胞介导的适应性免疫有关,而且与中性粒细胞、肥大细胞、单核/巨噬细胞、树突状细胞(dendritic cell,DC)等免疫细胞介导的固有免疫密切相关.因此本文旨在对免疫失衡及其介导的炎症反应在原发性肾小球疾病中的作用机制作一综述.
出处 《国际泌尿系统杂志》 2010年第5期704-708,共5页 International Journal of Urology and Nephrology
关键词 肾小球肾炎
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