3Iwasaki A, Kuwahara M, Yoshinaga Y, et al. Basic fibroblast growth factor(bFGF)and vascular endothelial growth factor (VEGF) levels,as prognostic indicators in Msclc. Eur Cardiothorac Surg, 2004, 25(3):443 448.
4Giaccone G,Herbst RS, Manegold C. Gefitinib in combination with gemcitabine and cisplatin in advanced non-small-cell lung cancer: a phase III trial-INTACT2. J Clin Oncol, 2004,22(5): 785-794.
5Han H, Silverman F, Santueci T, et al. Vascular endothelial growth factor expression in stage I non-small cell lung cancer correlates with neoangiongenesis and a poor prognosis. Ann Surg Oncol,2005,8(1) :72-79.
2[2]Makoto T, Masahiro T, Toshifumi T, et al. Frequent expression of the vascular endothelial growth factor mRNA in non-small-cell lung carcinoma [J]. Br J Cancer, 1999, 79: 363.
3[4]Lamoreaux WJ, Fitzgerald ME, Reinr A,et al. Vascular endothelial growth factor increases of gelatinase A and decreases release of tissue inhibitor of metalloproteinases by microvascular endothelial cells in vitro [J]. Microvasc Res,1998,55:29.
4[5]Zucker S,Minza H,Conner CE, et al. Vascular endothelial growth factor induces tissue factor and matrix metalloproteinases production in endothelial cells: conversion of prothrombin to results in progelatinase A activation and cell proliferation[J]. Int J Cancer,1998,75:780.
5[6]Claffay KP, Brown LP, Del Aguila LT, et al. Expression of vascular permeability factor/vascular endothelial growth factor by melanoma cells increases tumor growth, angiogenesis and experimental metastasis [J]. Cancer Res, 1996, 56: 172.
6[7]Karameris A, Panagou P, Tsilalis T, et al. Association of expression of MMP and TIMP with the metastatic potential of squamous cell lung carcinoma: a molecular and immunohistochemical study [J]. Am J Respir Int Care Med, 1997,156(6):1930.
7[8]Nawrochi, Polette M, Marchand V, et al. Metalloproteinase in no-small cell lung cancer patients [J]. Clin Cancer Res, 1999, 5(1):149.
8[10]Nakagawa H ,Yagihashi. Expression of type Ⅳ collagen and its degrading enzymes in squamous cell carcinoma of lung [J]. Cancer Res,1997,62:3164.
9[12]Zuker S, Lysik RM, Malik M, et al. Secretion of gelatinases and TIMP by human cancer cell lines and revertent cell lines: an invariant correlation with metastasis [J]. Int J Cancer, 1999, 52(3): 366.
10Ferrara N,Gerber H P,Lecouter J.The biology of VEGF and its receptors[J].Nature medicine,2003,9(6):669-675.
