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大剂量盐酸氨溴索配伍NCPAP在Ⅰ~Ⅱ级早产儿肺透明膜病中的应用 被引量:4

Effect of treatment of using large dose of ambroxol hydrochloride capsules with NCPAP on hyaline membrane disease in Ⅰ-Ⅱ grade premature infant
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摘要 目的:探讨大剂量盐酸氨溴索配伍鼻塞式持续气道正压通气(NCPAP)对Ⅰ~Ⅱ级早产儿肺透明膜病(HMD)的治疗作用。方法:给31例患HMD的早产儿静滴大剂量盐酸氨溴索30mg/(kg·d),同时给予NCPAP呼吸支持治疗。结果:31例患儿在联合治疗1~2h后血氧饱和度均上升至90%左右,呼吸窘迫明显缓解,皮肤转红润,三凹征减轻。结论:大剂量盐酸氨溴索配伍NCPAP能有效治疗I~Ⅱ级早产儿肺透明膜病。 Objective:To investigate the effect of treatment of using large dose of ambroxol hydrochloride capsules with nasal continuous positive airway pressure(NCPAP) on hyaline membrane disease in Ⅰ-Ⅱ grade premature infant.Methods:A total of 31 premature infants with hyaline membrane disease were treated by large dose of ambroxol hydrochloride capsules with NCPAP.Results:31 patients were clinical improved with SpO2 rising to about 90%,respiratory embarrassment and three depressions sign released.Conclusion:Large dose of ambroxol hydrochloride capsules with NCPAP has a curing effect on hyaline membrane disease in Ⅰ-Ⅱ grade premature infant.
作者 杨锐利 陈龙
出处 《中国当代医药》 2010年第25期52-53,共2页 China Modern Medicine
关键词 盐酸氨溴索 鼻塞式持续气道正压通气 早产儿肺透明膜病 Ambroxol hydrochloride capsules Nasal continuous positive airway pressure(NCPAP) Hyaline membrane disease
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