ABI、CAVI与冠状动脉病变关系临床研究

Relationship between coronary artery disease and CAVI and ABI

目的观察冠状动脉粥样硬化性心脏病(冠心病)患者踝臂指数(ABI)、心踝血管指数(CAVI)水平,并探讨其与冠状动脉病变之间关系。方法选取行冠状动脉造影的95例患者,其中35例为急性冠脉综合征(ACS)患者,30例为慢性稳定性冠心病(SCHD)患者,另30例为冠状动脉造影正常患者(对照组)。各组均检测ABI、CAVI指标,分析其与冠状动脉病变关系。结果 ACS组ABI水平明显低于对照组及SCHD组,差异有显著统计学意义(P均<0.01)。ACS组与SCHD组CAVI水平明显高于对照组(P<0.01),且ACS组CAVI水平高于SCHD组,差异有显著统计学意义(P<0.01)。结论冠心病尤其ACS患者动脉血管僵硬程度更高。

Objective To observe the levels of ankle-brachial index （ABI） and cardio-ankle vascular index （CAVI） in the patients with coronary heart disease （CHD） and discuss the relationship between coronary artery disease and ABI and CAVI. Methods The patients （n=95） undergone coronary angiography （CAG） were chosen,among them 35 with acute coronary syndrome （ACS group）,30 with chronic stable CHD （SCHD group） and 30 with normal CAG （control group）. The indexes of ABI and CAVI were detected by using arteriosclerotic instrument and the relationship between them and coronary artery disease was analysed. Results The ABI level was significantly lower in the ACS group than that in the control group and SCHD group,and the difference was statistically significant （all P0.01）. The CAVI level was significantly higher in the ACS group and SCHD group than that in the control group （P0.01）. In the ACS group CAVI level was higher than that in the SCHD group,and the difference was statistically significant （P0.01）. Conclusion The degree of artery stiffness may be higher in the patients with CHD,especially those with ACS.