布地耐德混悬液雾化吸入治疗小儿急性感染性喉炎的疗效评价

目的探讨布地奈德混悬液雾化吸入治疗小儿急性感染性喉炎的疗效。方法78例急性感染性喉炎并Ⅰ°～Ⅱ°喉梗阻的患者随机分为两组，治疗组43例，对照组35例。两组患者在吸氧、全身抗感染、退热等对症治疗基础上，治疗组加用布地耐德面罩雾化吸人治疗，对照组加用地塞米松静脉滴注治疗。分别于治疗4h、24h进行临床疗效判定，并且比较患者喉梗阻、声音嘶哑及咳嗽临床症状消失的时间，同时对两组患者住院天数进行比较。结果治疗4h、24h后，治疗组的疗效较对照组均有明显提高，差异具有统计学意义（P〈0．05）。治疗组患者喉梗阻消失时间较对照组明显缩短（P〈0．05），声音嘶哑及咳嗽症状两组比较差异无统计学意义（P〉0．05），两组患者住院天数比较差异无统计学意义（P〉0．05）。结论布地奈德混悬液雾化吸入治疗小儿急性感染性喉炎有良好疗效。

Objective To study the curative effects of atomizing inhalation of budesonide suspension treating acute infectious laryngitis of children. Method 78 cases with acute infectious laryngitis together with Ⅰ°～Ⅱ°laryngeal obstruction were divided into two groups random, 43 cases in the treated groups and 35 cases in the control group. Patients in the treated group were treated with atomizing inhalation of budesonide suspension; and patients in the control group were treated with intravenous drip of hexadecadrol. All the patients were treated with absorbing oxygen, anti - infecion all over the body and pyretolysis, 4h and 24h after the above - mentioned treatment, the clinical curative effects were decided respectively. The extinction times of clinical symptoms such as laryngeal obstruction, hoarseness and cough, and the hospital days of the patients of the two groups were compared. Results 4h and 24h after the above - mentioned treatment, the curative effects of the treated group were all significantly improved compared to the control group, the difference of which all had statistical significance （ P 〈 0. 05 ）. Compared to the control group, the extinction times of laryngeal obstruction of patients in the treated group significantly shortened （P 〈 0. 05 ） ; and the difference of symptoms of hoarseness and cough of patients between the two groups had no statistical significance （ P 〉 0. 05 ） ; and the difference of hospital days between the two groups had no statistical significance （ P 〉 0. 05 ）. Conclusion Atomizing inhalation of budesonide suspension treating acute infectious laryngitis of children has fine curative effects.