无创机械通气治疗急性心源性肺水肿临床研究

Noninvasive mechanical ventilation in the treatment of acute cardiogenic pulmonary edema

目的 评价BiPAP无创机械通气治疗急性心源性肺水肿病例的临床价值.方法 将兴宁市人民医院2008年10月-2010年5月收治的急性心源性肺水肿患者45例随机分为两组,对照组21例常规药物治疗,治疗组24例在常规药物治疗的基础上,应用BiPAP呼吸机面作者单位：514500 兴宁市人民医院心血管内科罩辅助通气,观察其前后症状、体征及动脉血气分析结果.结果 治疗组患者1h后呼吸、心率明显减慢SpO2、PaO2均明显改善,SBP和pH恢复正常,临床症状体征明显改善,与对照组比较差异有显著性（P＜0.05）.结论 无创机械通气治疗急性心源性肺水肿安全有效能迅速纠正缺氧、改善心功能,值得临床推广.

Objective To asses the efficacy of noninvasive nasal mask bi-level positive airway pressure （BiPAP） ventilation in acute cardiogenic pulmonary edema Methods 45patients with acute cardiogenic pulmonary edema hospitalized from October 2008 to May 2010 were randonly assigned to receive conventional medical treatment （21 patients,control group） or noninvasive nasal mask bi-level positive airway pressure （BiPAP） ventilation in addition to the conventional therapy （24 patients,study group）. The symptoms,signs,and the findings of blood gas analysis were noted. Results One hour after therapy,HR,RR,SpO2.and PaO2 were improved significantly in the study group SBP and PH were returned to normal the symptoms and signs were improved,with significant differences as compared with the control group. （P〈0.05）. Conclusions Noninvasive ventilation is a safe,effective method in the treatment of acute cardiogenic pulmonary edema with acute respiratory failure. It improves cardiac function and is worth popularizing.