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急性冠脉综合征患者血浆IL-17、hs-CRP及PWV的变化及意义 被引量：4

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摘要 目的观察急性冠脉综合征(ACS)患者血浆IL-17、高敏C反应蛋白(hs-CRP)水平和脉搏波传导速度(PWV),并探讨其临床意义。方法入选的30例ACS患者中有急性心肌梗死(AM I)14例、不稳定型心绞痛(UAP)16例,另择稳定型心绞痛(SAP)20例、健康对照者10例。采用ELISA法检测IL-17水平,胶乳增强免疫透射比浊法检测血浆hs-CRP水平,动脉硬化检测仪检测PWV。结果 AM I和UAP患者LL-17明显高于SAP和健康对照者(P<0.01);各冠心病患者血浆hs-CRP水平、PWV值均高于健康对照者(P<0.05)。hs-CRP与IL-17、PWV均呈正相关(r=0.696、0.652,P<0.05)。结论 ACS患者血浆IL-17、hs-CRP水平、PWV值均升高;IL-17可能参与动脉粥样斑块不稳定和ACS的发病;PWV值有望成为预测动脉粥样硬化程度的有效指标。
作者 杜娟 姜少燕 李健 安毅
机构地区 青岛大学医学院附属医院
出处 《山东医药》 CAS 北大核心 2010年第33期49-50,共2页 Shandong Medical Journal
关键词 急性冠脉综合征 白细胞介素17 C反应蛋白质 脉搏波传导速度
分类号 R541.4 [医药卫生—心血管疾病]
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参考文献7

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共引文献18

同被引文献34

  • 1吴兆增,骆美瑛,李梅,仇为民,史宝强,杨庆祥.冠心病患者细胞因子测定的临床意义[J].放射免疫学杂志,2006,19(4):293-295. 被引量：7
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引证文献4

二级引证文献17

山东医药
2010年 第33期

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