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多烯磷脂酰胆碱治疗慢性阻塞性肺疾病急性加重期肝损害的疗效研究 被引量:6

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摘要 目的观察多烯磷脂酰胆碱治疗慢性阻塞性肺疾病急性加重期(AECOPD)肝损害的疗效。方法根据肺功能将86例慢性阻塞性肺疾病急性加重期患者分为轻度、中度、重度和极重度4组,了解每组血ALT、AST受损情况;每组均给予多烯磷脂酰胆碱注射液697.5mg溶于5%葡萄糖溶液250m l中静脉滴注,1次/d,疗程10d,观察治疗前后血ALT、AST的变化。结果 AECOPD分级越高,血ALT、AST水平越高,差异具有统计学意义(P<0.05)。多烯磷脂酰胆碱治疗后四组血ALT、AST均有下降,改善情况均有显著性差异(P<0.05)。结论 AECOPD受累程度越高,肝功能损害越严重。多烯磷脂酰胆碱治疗AECOPD肝损害有效。
作者 徐英
出处 《实用心脑肺血管病杂志》 2010年第10期1426-1427,共2页 Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
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