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中性粒细胞弹性蛋白酶与急性肺损伤 被引量:2

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摘要 急性肺损伤(ALI)是机体遭受严重创伤、休克、酸中毒及严重感染等因素引起的一类继发性、弥漫性肺实质损伤性疾病,临床表现为顽固性低氧血症、弥漫性肺部浸润及肺顺应性下降,进一步恶化可导致急性呼吸窘迫综合征(ARDS)。ALI病死率高达40%~60%,其发病机制并未完全阐明,一般认为与肺部炎症细胞聚集并释放炎症介质,损伤肺微血管内皮细胞及上皮细胞有关。
出处 《感染.炎症.修复》 2010年第2期118-122,共5页 Infection Inflammation Repair
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