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唑来膦酸静滴辅助放化疗治疗肺癌骨转移28例临床观察 被引量:20

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摘要 目的观察唑来膦酸静滴辅助放化疗治疗肺癌骨转移的临床疗效。方法对28例肺癌多发性骨转移患者,采用唑来膦酸4 mg加入0.9%氯化钠100 ml中静滴联合6 mV X线局部放疗和GP、NP、TP或EP方案化疗。结果全组中26例完成治疗,2例因并发脑转移死亡。止痛效果:CR 20例,PR 6例,MR 1例,NR 1例,总有效率为92.9%;骨转移灶:CR 4例,PR 8例,NC 11例,PD 5例,总有效率为42.9%。不良反应均能耐受。结论唑来膦酸静滴辅助放化疗治疗肺癌骨转移效果较好。
机构地区 乳山市人民医院
出处 《山东医药》 CAS 北大核心 2010年第30期105-106,共2页 Shandong Medical Journal
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