摘要
环孢素(CsA)是从土壤真菌中提取的一种多肽,因具有免疫特性,通过下调多种细胞因子的基因转录而抑制免疫反应.且通过影响。肾小球的通透性而减少蛋白尿。目前多用于治疗激素及细胞毒药物无效的难治性肾病综合征(NS),但因其有肝肾毒性、高血压、高尿酸血症、多毛及牙龈增生等不良反应而受到广泛限制。
出处
《中国药物与临床》
CAS
2010年第9期1065-1067,共3页
Chinese Remedies & Clinics
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