脉冲电磁场促进周围神经再生的实验研究

An experimental study on pulsing electromagnetic field therapy in peripheral nerve regeneration

目的：探索脉冲电磁场对周围神经再生的影响及其作用机理。方法：用ＳＤ雄性大鼠２４只，在距梨状肌下缘约１ｃｍ处切断坐骨神经后原位吻合，随机分成１／２、１、２月３组，每组又分成对照和实验组，实验组用微电脑电磁脉冲发生器进行治疗，两组均在不同时间通过肉眼观察、肌电图检测及取材组织学检测。结果：实验组较对照组Ｗａｌｅｒｉａｎ变性明显、加速、血管增生明显、纤维组织增生轻、神经再生及传导速度加快。

Objective : To explore the effects of pulsing electromagnetic field on peripheral nerve regeneration as well as the mechanism were determined.Method:Twenty four SD male rats were used in this study. Their sciatic nerves were cut at 1cm under the musculus piriformis then were anastomosed. The rats were divided into three groups (0.5 month ,one month and two months) at random.Then each of them was divided into the study subgroup and the control subgroup . The electromagnetic field was used only for the study group.EMG, nerve observation and histologic examination were performed for these groups repectively.Result:In the study subgroup, accelerated Wallerian's degeneration, obvious blood vessels proliferation, mild fibrous tissue proliferation and accelerated nerve regeneration were seen than the control subgroup.Conclusion:The pulsing electromagnetic field could improve peripheral nerve regeneration.