摘要
目的:探讨我院喹诺酮类抗菌药药品不良反应(ADR)的发生情况及引发ADR的相关因素,为该类药物的临床合理应用提供参考。方法:我院2004年6月～2009年9月共收集到934例ADR,将其中149例喹诺酮类抗菌药ADR进行分类汇总,统计分析。结果:149例喹诺酮类抗菌药ADR中,静脉滴注给药者最多,占总例数的59.60%;注射用左氧氟沙星引起的ADR居首位;皮肤及附件损害是ADR的最主要表现,占总例数的43.75%(70例),严重的ADR8例。结论:喹诺酮类药物ADR多见,应加强对该类药物的监管,减少ADR的发生,促进其合理使用。
Objective： To observe the occurrence of ADRs related to quinolones in our hospital and analyze its correlative factors in order to provide strategies for clinical rational use of drugs. Methods ：934 ADR cases collected in the hospital from June 2004 to September 2009 were categorized, and statistically analyzed. Results：In the 149 ADR cases re- lated to quinolones, the intravenous drip was the main route of administration which accounted for 59.60%. Levofloxacin injection was No. 1 drug causing ADRs. The damages of skin and its appendants were the most common manifestation, which accounted for 43.75% （70 cases）. There were 8 serious ADR cases. Conclusion：ADRs related to quinolones were common. The regulation of quinolones should be strengthened so as to decrease the occurrence of ADRs and guarantee the rational use.
出处
《药物流行病学杂志》
CAS
2010年第9期501-503,共3页
Chinese Journal of Pharmacoepidemiology
关键词
喹诺酮类
药品不良反应
现状
对策
Quinolones
Adverse drug reactions
Current situation
Strategies
