摘要
目的:研究康艾注射液对晚期肝癌患者生活质量的影响。方法:68例晚期肝癌患者随机分为2组。两组均给予一般护肝治疗;治疗组加康艾注射液50 mL静脉滴注,qd。2个月为1个疗程,记录治疗前后两组患者的肿瘤直径的差值、静脉癌栓、远处转移、临床症状、行为状态评分(采用Karnofsky评分标准)及生存时间。结果:对照组肿瘤大小增长速度明显高于治疗组(P<0.05);合并静脉癌栓及远处转移例数对照组明显多于治疗组(均P<0.05);治疗组行为状态评分较用药前明显增高(P<0.01),对照组明显下降(P<0.01);治疗组生存时间较对照组明显延长(P<0.01);治疗组临床症状改善情况明显优于对照组(P<0.01或P<0.05)。结论:康艾注射液能提高晚期肝癌患者的生活质量。
Objective: To study the effect of Kangai injection on quality of life in patients with advanced hepatic cancers.Methods: A total of 68 patients with advanced hepatic cancer were divided into 2 groups.They were treated with either symptomatic therapy alone or combined with Kangai injection(50 mL,intravenous infusion,once daily for 2 months).The difference of tumor diameters,tumor emboli in veins,distant metastasis,clinic symptoms,behavior scales(evaluated by Karnofsky scale) and survival time were observed before and after the treatment.Results: The growth speed of tumor was faster in the control group than in Kangai group(P0.05).The patients complicated with tumor emboli in veins and distant metastasis in the control group were more than those in Kangai group(P0.05).The behavior scales descended significantly in control group(P0.01).The scales ascended(P0.01) and survival time obviously prolonged(P0.01) in Kangai group as compared to control.The clinic symptoms were also significantly improved in Kangai group(P0.01 or 0.05).Conclusion: Kangai injection can improve the quality of life in patients with advanced hepatic cancers.
出处
《中国新药杂志》
CAS
CSCD
北大核心
2010年第17期1575-1577,1584,共4页
Chinese Journal of New Drugs
关键词
晚期肝癌
中医药治疗
生活质量
advanced hepatic cancer
Chinese medicine therapy
living quality