大气污染对儿童非特异免疫功能影响的研究

STUDY OF AIR POLLUTION INFLUENCING CHILDREN'S NONSPECIFICIMMUNOLOGICAL FUNCTION IN INDUSTRY AREA

探讨天津市工业区大气污染对儿童非特异性免疫功能的影响，为大气环境综合治理提供卫生学依据。方法：把天津市某工业区作为污染区与对照区进行了环境流行病学调查，调查对象为７～１２岁学龄儿童。结果：工业污染区中ＳＯ２、ＮＯｘ、ＴｓＰ、ＣＯ超标率分别达５５．５５％、３４．４５％、９３．７８％、３２．２５％；分别是对照区的４．５５倍、４．１５倍、１．３０倍、１．５３倍；污染区儿童非特异性免疫指标唾液溶菌酶活性、ＳＩｇＡ含量、鼻粘膜细菌总数及溶血性链球菌数目与对照区比均有非常显著性差异（Ｐ＜０．００１或Ｐ＜０．０１）和显著性差异（Ｐ＜０．０５）。结论：提示污染区大气污染已对儿童健康状况产生明显危害。

Objective: To study the influence of air pollution on children's nonspecific immunological function in Tianjin Industry Area,and provide hygiene basis for tackling air environment in a comprehensive way.Methods: To carry out on environment epidemiology investigation in Tianjin Certain Industry Area and relevant comparison area and the investigate object is school children with aged 7￣12. Results: The results showed that in pollvted area the exceed standard rate of SO2,NOx,TsP,CO are 5555%,3445%,9338% and 3225% respectively.Correspondingly in comparison area are 455,415, 130 and 153 times as that in polluted area respectively.Childred's nonspecific immunological function targets are spittle bacteriolysin ferment activate,SIgA content,nose mucous bacterium total amount,heamolysis streptococcus amount.All these targats in polluted area have great remarkable discrepancy (P<0001 or P<001)and remarkable discrepancy (P<005) comparing with relevant comparison area. Conclusion: These results indicated that air pollution had been obviousy detrimental to children's health in this area.